Probiotic Powder Inhalation Shows Potential in Reducing Lung Inflammation and Improving Pulmonary Function

 

 

 

 

 

 

 

 

 

 

 

Probiotic Powder Inhalation

 

Shows Potential in Reducing Lung Inflammation and Improving Pulmonary Function

 

 

 

 

 

 

 

 

 

https://n.news.naver.com/article/296/0000081124?cds=news_media_pc&type=editn

 

 

 

 

 

Live probiotics, commonly found in yogurt, fermented drinks, kombucha, kimchi, and traditional fermented foods, may have a new therapeutic role in treating lung diseases.

 

A recent study conducted by researchers at the University of Alabama at Birmingham (UAB) suggests that inhaling a powder mixture of live probiotics, specifically Lactobacillus, could reduce lung inflammation and improve pulmonary function in conditions such as chronic obstructive pulmonary disease (COPD) and bronchopulmonary dysplasia (BPD).

 

 

 

 

https://n.news.naver.com/mnews/article/123/0002122105

 

 

 

The study, titled "A Lactobacilli-based inhaled live biotherapeutic product attenuates pulmonary neutrophilic inflammation," was published in the prestigious journal Nature Communications.

 

It highlights the potential for developing a new biotherapeutic drug using live probiotics, based on preclinical trials conducted on mice.

 

 

 

 

https://www.wikitree.co.kr/articles/977626

 

 

 

Bronchopulmonary dysplasia (BPD) is a serious lung condition that affects newborns who require oxygen or mechanical ventilation due to respiratory distress at birth.

 

Chronic obstructive pulmonary disease (COPD) primarily affects older adults, especially smokers, and is responsible for approximately 3 million deaths globally each year.

 

 

 

 

 

https://www.wikitree.co.kr/articles/977626

 

 

 

 

Dr. Amit Gaggar, the lead author of the study and a specialist in respiratory and allergy research at UAB, explained that inhaling live probiotics reduces inflammation caused by neutrophils, a type of white blood cell.

 

This process decreases inflammatory markers in the lungs associated with both COPD and BPD.

 

The researchers found that probiotics play a significant role in regulating the activity of proteases, enzymes involved in the breakdown of proteins, which are linked to lung damage caused by chronic neutrophilic inflammation.

 

By controlling these proteases, probiotics help protect the lung’s air sacs from further damage.

 

 

 

 

https://www.fashionbiz.co.kr/article/206799

 

 

 

The team had previously discovered in 2016 that probiotics could offer protective benefits in the lungs and might be used in treating chronic lung diseases.

 

This earlier research focused on infants with severe bronchopulmonary dysplasia.

 

In the current study, they further explored how probiotic therapy reduces the onset of secondary diseases and demonstrated the safety and efficacy of live biotherapeutic treatments in mouse models of COPD and BPD.

 

 

 

 

 

https://digitalchosun.dizzo.com/site/data/html_dir/2024/02/28/2024022880233.html

 

 

 

The next step for the research team will be to conduct clinical trials to evaluate the effectiveness and safety of this probiotic-based therapy in humans.

 

If successful, this innovative approach could offer a promising new treatment option for patients suffering from chronic lung diseases, helping to alleviate symptoms and improve their quality of life.

 

 

 

 

https://www.news2day.co.kr/article/20240822500017

 

 

 

 

This groundbreaking research could mark a significant advancement in the treatment of lung conditions, offering a natural and novel approach through the use of live probiotics.

 

 

 

 

 

 

 

 

 

 

 

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